Stop Dht
Author: Andrew AdlerTestosterone, a male hormone, is converted into DHT or Dihydrotestosterone in various tissues of human body and the skin. The enzyme 5 alpha reductase converts
testosterone into its more potent form DHT. Baldness is largely the result of various hormones interacting over time with those hair follicles that are vulnerable to their effects. DHT is primarily responsible for causing hair loss known as Androgenetic Alopecia in men and women. Whilst there are many other
causes of hair loss the primary reason is still DHT!
For men experiencing thinning hair their follicles on the top of the head are genetically vulnerable to baldness. Over time, the hormone DHT acts upon these genetically vulnerable follicles. This hormone binds with the receptor sites of these vulnerable follicles and causes a miniaturization of the hair shaft and follicle over time. The process of
hair loss gradually breaks down the follicles' ability to grow healthy, thick hair.
DTH can be slowed or even stopped by hair loss drugs like
Propecia. These drug works by either inhibiting the creation of DHT in our bodies or by blocking them from attaching to the androgen receptors on the hair follciles. By reducing the amount of DHT or by blocking the DHT and stopping it from effecting the hair follicles it is possible to
prevent hair loss . Propecia is US Food and Drug Administration (FDA) approved drug and can only be prescribed by a physician.
Other drugs belonging to the group known as 5 alpha reductase inhibitors are used for treatment of problems stemming from DHT. This group includes finasteride (sold under the names Proscar for BPH and Propecia for androgenic alopecia as well as in generic formulation) and dutasteride (sold under the name Avodart).
Alternative treatments used to inhibit
DHT. include dietary supplementation with, or topically administered preparations of, saw palmetto berry extracts for example. Unlike most known 5-alpha-reductase inhibitors, saw palmetto induces its effects without interfering with cellular capacity. Saw palmetto extract has been demonstrated to inhibit both isoforms of 5-alpha-reductase unlike finesteride, which only inhibits the predominant isoenzyme of 5-alpha-reductase. Moreover, the chemical equol, derived by consuming foods rich in soy isoflavones by persons with certain digestive-tract bacterial flora, appears to have an androgen-inhibitive effect too.